Bishoujo ni TS Tensei shita kara Daijoyuu wo Mezasu!

Keiji Matsuda is a 39-year-old man who, due to failing health, has become bedridden. Having no friends to help him and his family ostracizing him, Keiji is left with nothing to do but regret his life. Perhaps, he thinks, it would have been better if he was born a girl instead. The moment he had that thought, he heard a voice out of nowhere and his consciousness fell into darkness... He woke up to a familiar ceiling, now in the body of a baby. Indeed, Keiji has been reincarnated as Sumire Matsuda—the person he would have been if he was born female. Now given a new opportunity, Sumire decides that she will live life better... and use her good looks to become an actress along the way.

(Source: MU)